Artemisinin derivatives series
双氢青蒿素Dihydroartemisinin
Synonym: Dihydroartemisinin; alpha-Dihydroartemisinin; Artenimol
CAS NO.: 81496-81-3.
Art No.:AHG0029A
Molecular formula：C15H24O5
Molecular weight：284.35
This product is a derivative of artemisinin, it is suitable for various symptoms of malaria control, especially it has good effect on chloroquine and pernicious malaria. It has strong and fast killing effect on plasmodium falciparum erythrocytic stage, it can quickly control the clinical seizures
and symptoms.
Quality standard: CP2010
Quality index：
Property: white needle like crystal.
Assay: 98.0%-102.0%(HPLC)
Application: Anti malaria API
蒿甲醚Artemether
CAS NO.: 71963-77-4.
Art No.:AHG0030A
Molecular formula：C16H26O5
Molecular weight：298.4
Synonym: :Artemetherum、Artemtherin, Dihydroartemisinin methyl ether ; Dihydroqinghaosu methyl ether
This product is a killing agent with high performance and quick effect for plasmodium falciparum erythrocytic stage. It is suitable for all types of malaria, but mainly for emergency treatment of chloroquine resistant falciparum and severe falciparum malaria. The effects takes fast, and short-term efficacy is good.
Quality standard：CP2010
Quality index：
Property：white crystalline powder
Assay：98.0%-102.0%(HPLC)
Application：Anti malaria API
蒿乙醚Arteether
Synonym：0-Ethoxydecahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin;
CAS NO.: 75887-54-6
Art No.:AHG0031A
Molecular formula：C17H28O5
Molecular weight：312.4
The Plasmodium removal effect for different types of malaria is good, its effects takes fast and it is easy to use, it also can be used for the patients who can not taking other oral antimalarial drugs. It has direct killing effect on Plasmodium falciparum erythrocytic stage but no effect on the pre erythrocytic Plasmodium and Organization stage Plasmodium.
Quality standard：IP
Quality index：
Property：white crystalline powder
Assay：98.0%-102.0%(HPLC)
Application：Anti malaria API
青蒿琥酯Artesunate
Synonym: Plasmotrin, Arsumax; Artesunato; Artesunato [inn-spanish]; Artesunatum;
CAS NO.: 88495-63-0.
Art No.:AIE0012A
Molecular formula：C19H28O8
Molecular weight：384.4
Artesunate is a commonly used anti parasite drug, it is reduced artemisinin succinic acid monoester, it is derivatives of artemisinin with sesquiterpene lactones structure, its’ function on Plasmodium is stronger than that of artemisinin, it is also effective on chloroquine resistant strains.
Artesunate has strong killing effect on Plasmodium falciparum asexual body, it can quickly control the attack of malaria. This product can treat vivax malaria, the malignant mean parasite clearance time is faster than chloroquine. There is not any toxic and side effects in clinical treatment.
It is suitable for cerebral malaria and all kinds of severe malaria.
Quality standard：CP2010
Quality index：
Property：white crystalline powder
Assay：98.0%-102.0%(HPLC)
Application：Anti malaria API
本芴醇Lumefantrine
Synonym: Benflumetol
CAS NO.: 82186-77-4
Art No.:AHG0032A
Molecular formula：C30H32Cl3NO
Molecular weight：528.9
Lumefantrine (benflumetol) is a kind of mefloquine new drug which was invented in our country, it has obvious killing effect on plasmodium vivax sexual body and asexual body, it has good effect of preventing malaria tertiana, it also has killing effect on plasmodium falciparum asexual body, but the effect takes slowly.
It is mainly used to treat falciparum malaria, especially suitable for chloroquine resistant falciparum malaria. Combined with artemether, their anti malaria effects can be complementary, lumefantrine can kill insect thoroughly with lasting effect, but the symptoms controlling speed is slow.
Quality standard：CP2010
Quality index：
Property：yellow crystalline powder
Assay：98.0%-102.0%(HPLC)
Application：Anti malaria API
本芴醇中间体4步Step4(or N-1 step)Intermediate of Lumefantrine
Synonym：2,7-Dichloro-α-(Dibutylamino)methyl-9H-Fluorene-4-Methanol
CAS NO.: 69759-61-1
Art No.:AJA0131A
Molecular formula：C23H29Cl2NO
Molecular weight：394
Quality standard：CP2010
Quality index：
Property：light yellow crystalline powder
Assay：>98.0%(HPLC)
Application: Step4(or N-1 step)Intermediate of Lumefantrine
本芴醇中间体3步Step3(orN-2step)Intermediate of Lumefantrine
Synonym：2-(2,7-Dichloro-9H-fluoren-4-yl)-Oxirane
CAS NO.: 53221-14-0
Art No.:AJA0132A
Molecular formula：C15H10Cl2O
Molecular weight：277
Quality standard：CP2010
Quality index：
Property：off white crystalline powder
Assay：>97.0%(HPLC)
Application: Step3(orN-2step)Intermediate of Lumefantrine
磷酸萘酚喹Naphthoquine Phosphate
Synonym：Naphthoquini phosphas
CAS NO.:173531-58-3
Art No.:AHF0023A
Molecular formula：C24H28ClN3O·2H3PO4·2H2O
Molecular weight：641.98
Naphthoquine phosphate has killing effect on various plasmodium falciparum schizont and some plasmodium gametocyte and organisation of protozoa, it has good cure effect on drug-resistant plasmodium and long-term preventive effect on plasmodium.
Naphthoquine phosphate is suitable for treatment of Plasmodium falciparum, malaria tertiana and drug resistant plasmodium.
Quality standard：CP
Quality index：
Property：light yellow or yellow crystalline powder
Assay：> 98.5%(HPLC)
Application：Anti malaria API
磷酸哌喹Piperaquine Phosphate
Synonym: Piperaquine tetraphosphate tetrahydrate
CAS NO.: 4085-31-8
Art No.:AIE0018B
Molecular formula：C29H32Cl2N6·4H3PO4·4H2O
Molecular weight：999.56
The antimalarial effect of this product is similar with chloroquine. After oral absorption it is stored in the liver, then it is slowly released into blood, it has a long-term preventive effect. It is mainly used for inhibitive prevention of symptoms of malaria and treatment of malaria. Now it is also used in prevention and treatment of silicosis.
Quality standard：CP2010
Quality index：
Property: off white to light yellow crystalline powder
Assay：98.0%
Application：Anti malaria API