Diosgenin and its derivatives intermediate of steroid hormone products series
Time：2014-04-11 Hits：4848
Diosgenin is the important basic raw material of steroid hormone drugs. Steroid hormone has strong pharmacological effects of anti-infection, anti-allergic, anti-virus and anti-shock, it is important medicine to treat rheumatism, cardiovascular, lymphatic leukemia, cell encephalitis, skin diseases and tumor and to save critical patients; It is raw material of acetate dehydropregnenolone which is the important intermediates of steroid hormone drugs and through it all kinds of steroid drugs can be synthesized, such as hydrocortisone, prednisone, norethindrone, fluocinolone, dexamethasone and so on.
Diosgenin is called medicinal gold in pharmaceutical industry, the medicinal value is very high and the uses are broad. Chinese Diosgenin is steady growing basic materials of hormone in the world, Chinahas been in dominant and monopolistic position. The diosgenin extracted from turmeric is important basic raw material in pharmaceutical industry to synthesize hormone, it can be used in synthesis of intermediates including dienes and 16，17-a-Epoxyprogesterone , it’s also the starting material of bulk drug hormone, such as progestin, prednisone acetate, budesonide, methyl testosterone, cyproterone, androstendione, betamethasone, dehydroisoandrosterone and others .These drugs are used widely.
Shanghai Seebio provides a variety of diosgenin and derivatives including steroid hormone products in different specification, we will dedicate to serve for all the customers.
| Product name/CASN | Molecular formula/MW | Specification | Product Description |
|
Diosgenin 512-04-9 |
C27H42O3 MW: 414.6206 |
Complied to Ministerial level standard Melting point ≥195℃ |
Properties: white or slight yellow crystalline powder, no obvious oil lost taste or other strange smell. Uses: the main raw materials to synthesize hormone and birth control drugs. |
|
16-Dehydropregnenolone Acetate 979-02-2 |
C23H32O3 MW: 356.50 |
Assay：≥98% (HPLC) Melting point：≥165℃ Loss on drying：≤0.5% |
Properties: White crystalline powder， no strange smell，stable in air, easily soluble in Ethanol and methanol, insoluble in water. Uses：it is the intermediates of Steroid hormone, and it can be used to make Corticosteroids, anabolic steroids, androgens, female hormone, luteinizing hormone drugs |
|
Pregnenolone Acetate 1778-02-5 |
C23H34O3 MW: 358.52 |
Melting point：≥145℃ Assay：≥98% Loss on drying：≤0.5% |
Uses：it is used in the synthesis of intermediates and drugs of steroids. |
|
Pregnenolone 145-13-1 |
C21H32O2 MW: 316.48 |
Melting point：180℃ Assay：≥99.0% Moisture：≤0.5% |
Properties: White or near white crystalline powder Uses：it is used in the synthesis of intermediates and drugs of steroids, it is the intermediates of progesterone, antiflamison pregnenolone acetylsalicylate, deoxycorticosterone and oher hormone drugs |
|
16,17-a-Epoxyprogesterone 1097-51-4 |
C21H28O3 MW: 328.45 |
Melting point：201 ℃ Assay：≥98.5% loss on drying：≤0.5% |
Properties: White or near white crystalline powder，odorless，slightly soluble in Ethanol , methanol and methylbenzene Uses: the main raw materials to synthesize hormone and other steroid hormone drugs. |
|
17a-Hydroxy -progesterone acetate 302-23-8 |
C23H32O4 MW: 372.50 |
Melting point：240℃ loss on drying：≤0.5% Assay：≥98.5% optical rotation：71—75° |
Properties: White needle-like crystal, odorless, tasteless early and then has a lasting bitterness. Uses: Intermediates of prednisone acetate. Itself is a kind of anti-inflammatory agent which can treat Adrenal cortical function disorder, rheumatoid arthritis, rheumatism and lupus etc. |
|
progestin 57-83-0 |
C21H30O2 MW: 314.47 |
Melting point：126℃ optical rotation：+27°～+30° Assay：(HPLC)：97.0%---103.0% Moisture：≤0.5% |
Appearance: white or almost white crystalline powder Uses: it belongs to steroid hormone and progesterone drugs, it is main raw material to synthesize progestin products. |