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BionatFP NA98 (Protamine) :Natural Food Preservative

Time:2014-09-23 Hits:2439

Seebio Natural Food Preservative: BionatFP NA98 (Protamine)

Description
Protamines are small, arginine-rich, nuclear proteins (Molecular weight around 4,000- 5,000) that replace histones late in the haploid phase of spermatogenesis and are believed essential for sperm head condensation and DNA stabilization. They may allow for denser packaging of DNA in spermatozoon than histones, but they must be decompressed before the genetic data can be used for protein synthesis. However, in humans and maybe other primates, 10-15% of the sperm's genome is packaged by histones thought to bind genes that are essential for early embryonic development.

Function
In body, Protamine is digested by enzymes. Therefore, its character is based on its amino acid composition. 2/3 of Amino acid in Protamine is Arginine, which has functions below;
- Improve liver functions
- Improve stamina and fertility.
- Immune-enhancing effect
- Lower blood pressure
- Against arteriosclerosis
Arginine is not an essential amino acid, but it is an important amino acid for children's growth. Arginine is also good for adults who take too much meat products.

Application
As a pharmaceutical product, Protamine works to neutralize Heparin, keeps continued antihyperglycemic effects together with Insulin, and also works to against fat absorption in the intestine.

In gene therapy, protamine sulfate's ability to condense plasmid DNA along with its approval by the FDA have made it an appealing candidate to increase transduction rates by both viral and nonviral (e.g. utilizing cationic lipids) mediated delivery mechanisms.

Protamine has been widely used as a natural food preservative since 1980s. It has a broad spectrum of antibacterial activity. As an arginine-rich protein, it is non-toxic and has a high nutritional value. The main components in foods, such as protein, fat and carbohydrates, have little effect on protamines, which is suitable in food process. Recent applications of protamine include its use as a preservative in dairy, egg, vegetable and seafood preservation.

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Seebio Natural Food Preservative: BionatFP NA98 (Protamine)


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