L-proline is an important amino acids to synthesize human proteins, it has curative effect on hypertension,
it has been widely used in food and pharmaceutical industry.It can generate a special flavor substances when heating with sugaar and amino acids - carbonyl reaction take place.
Chemical & Physical Properties
mp 228 °C (dec.)(lit.)
alpha -85.5 º (c=4, H2O)
density 1.35
FEMA 3319
refractive index -85 ° (C=4, H2O)
storage temp. Store at RT.
solubility H2O: 50 mg/mL
form powder
Water Solubility soluble
Merck 14,7780
BRN 80810
Stability: Stable. Incompatible with strong oxidizing agents.
Quality Standard
Item
|
CP2010
|
EP5
|
AJI92
|
USP24
|
Assay
|
≥99.0%
|
98.5~101.0%
|
98.5~101.0%
|
98.5~101.5%
|
pH
|
5.9~6.9
|
|
5.9~6.9
|
|
Specific rotation[a]D020
|
-84.5°~-86.0°
|
-84.0°~-86.0°
|
-84.5°~-86.0°
|
|
[a]D025
|
|
|
|
-84.3°~-86.0°
|
Transmittance(T430)
|
clear & colorless
≥98.0%
|
clear & colorless
≥98.0%
|
≥98.0%
|
|
Chloride(Cl)
|
≤0.02%
|
≤0.02%
|
≤0.02%
|
≤0.05%
|
Ammonium(NH4)
|
≤0.02%
|
≤0.02%
|
≤0.02%
|
|
Sulfate(SO4)
|
≤0.02%
|
≤0.03%
|
≤0.02%
|
≤0.03%
|
Iron(Fe)
|
≤10ppm
|
≤10ppm
|
≤10ppm
|
≤30ppm
|
Heavy metals(Pb)
|
≤10ppm
|
≤10ppm
|
≤10ppm
|
≤15ppm
|
Other amino acids
|
≤0.5%
|
≤0.5%
|
Conforms
|
Conforms
|
Loss on drying
|
≤0.30%
|
≤0.50%
|
≤0.30%
|
≤0.40%
|
Residue on ignition
|
≤0.10%
|
≤0.10%
|
≤0.10%
|
≤0.40%
|
Endotoxin
|
≤10EU/g
|
|
|
|
|
Function:
Has curative effect on hypertension
Application:
L-proline is an important amino acids to synthesize human proteins, it is also an important raw material for amino acid infusion, and the main intermediates to synthesize of captopril, enalapril and other first-line antihypertensive drugs, it has been widely used in food and pharmaceutical industry.
It can be used as nutritional supplements, flavors. It can generate a special flavor substances when heating with sugaar and amino acids - carbonyl reaction take place.
【Package and storage】:
Packing: inner packing is Aluminum plastic composite bag, packing 25kg fiber drum
Storage: Sealed, valid for two years