Cytotoxicity: IC 50 retinol 25μM, retinol retinoic acid ester is 40μM (60% higher than retinol), retinoic acid is a prescription drug, and it is forbidden to be used in personal care (IC 50 is a certain concentration of certain substance to induce 50% of the amount of cell apoptosis, used to measure the ability of the substance to induce apoptosis. The higher the cell toxicity, the weaker);
Biological activity: Retinol retinoate retains the cyclic end groups and side chain alkenyl groups, and still has the biological activity of retinol and retinoic acid. In vivo tests show that the ability to promote skin regeneration is better than retinol and retinoic acid;
Improve the optical stability and chemical stability of retinol, while reducing the irritation of retinol and retinoic acid.