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Glyceryl Glucoside: The Star Ingredient in Skincare

Time:2024-07-10 Hits:254
Glyceryl Glucoside (CAS: 22160-26-5) is renowned as both a "star ingredient" and a "skin defense champion" in the skincare industry. This multifaceted compound has also emerged as a trending sensation, celebrated for its impressive range of benefits.
 
 
 
Product properties
Structural formula
C9H18O8
Molecular weight
254.23
Color
White powder
Purity
≥90%
2-α-GG content
40-55%
Glycerol content
≤1%
PH
5-7
Packaging
1kg, 25kg
Storage
Keep away from light and ventilated. Store in a cool place (2-10°C).
 
Glyceryl Glucoside: Unveiling the Secret of Resurrection Grass's Vitality
In the harsh environment of the South African grasslands, a remarkable plant known as Milo, also referred to as South African Phoenix Grass or Immortal Grass, thrives. Milo trees can endure extremely arid conditions and quickly revive after rainfall. The secret to this remarkable resilience lies in the glyceryl glucoside they contain. Studies have shown that glyceryl glucoside can reactivate Milo cells that have been exposed to prolonged drought, restoring their vitality. It protects and regenerates cells by safeguarding cell membranes and specific proteins, increasing intracellular osmotic pressure, and inhibiting water loss.
 
Application Value of Glyceryl Glucoside
Excellent Moisturizing Ability: Glyceryl glucoside significantly increases the expression of aquaporin AQP3, enhancing the skin's water retention function, reducing water loss, and providing long-lasting moisturizing effects.
 
Skin Permeability: Glyceryl glucoside has excellent skin permeability, effectively reducing water loss and improving issues such as dryness, dullness, and fine lines.
 
Multiple Physiological Activities: It activates and promotes cell regeneration, enhances cell vitality, accelerates cell metabolism, boosts antioxidant capacity, and promotes collagen synthesis.
 
Applications in Multiple Fields: Glyceryl glucoside is also non-cariogenic, can treat diabetes, and promotes the growth of probiotics, making it a potential health food additive in the future.
 
 
Wide Application Fields of Glyceryl Glucoside
 
Cosmetics/Daily Necessities
-  Glyceryl glucoside (GG) provides excellent cleansing and moisturizing effects and is often used as a glycerol substitute in cosmetics. As a low-toxic alternative to cryopreservatives, GG demonstrates significant cryopreservation capabilities at concentrations of 30%-40% (v/v). In cytotoxicity tests, DMSO exhibited the highest cytotoxicity, while GG showed a stronger cell-killing effect at concentrations above 4% (v/v). However, genotoxicity studies have found that while glycerol induces genotoxic reactions, GG does not significantly induce genotoxicity, making it a safer alternative in cosmetics and cryopreservation.
 
-  GG also improves dehydrated skin conditions by increasing the expression of aquaporin AQP3. Studies on human keratinocytes have shown significant improvements in AQP3 mRNA and protein levels. Volunteer studies using a formula containing 5% GG demonstrated effective epidermal penetration, increased AQP3 mRNA expression, and significant reduction in epidermal water loss.
 
Biomedicine
-  Glyceryl glucoside has shown significant moisturizing properties, making it effective in treating dry skin, especially when combined with natural moisturizing factors and ceramides. GG helps maintain skin hydration by attracting and retaining moisture, enhancing skin barrier function, and reducing moisture loss. Topical formulas containing GG have been effective in relieving symptoms of Sjögren's disease by improving moisture retention and barrier function.
 
-  For mild to moderate psoriasis, emollients containing GG, 10% urea, and ceramides significantly improve the quality of life and clinical symptoms. In a prospective observational study, patients using the emollient for four weeks showed a 35% improvement in quality of life and a 19% improvement in clinical symptoms. These ingredients work synergistically to enhance skin barrier function, improve hydration, and relieve psoriasis symptoms.
 
-  New GG moisturizers reduce transepidermal water loss more effectively than commonly used ceramide moisturizers, providing superior skin moisturizing effects. These moisturizers combine GG, ceramides, and natural moisturizing factors to significantly enhance skin barrier function and alleviate dryness symptoms. Preliminary research indicates that GG is more effective than glycerin in reducing water loss, making these moisturizers a powerful tool in treating Sjögren's disease.
 
-  In treating Sjögren's disease in children with chronic kidney disease, moisturizers containing GG, urea, natural moisturizing factors (NMF), and ceramide significantly reduce the severity of dry skin and improve skin moisture and barrier function compared to 5% urea emulsion. The study found no significant impact on blood urea nitrogen (BUN) and creatinine levels with the use of urea products, and no adverse reactions were reported, indicating that both products are safe and effective.
 
Food
-  GG is used as an emulsifier and stabilizer in various foods, including ice cream, candy, chocolate, and dairy products. Its unique glycoside chemical structure provides significant prebiotic properties, promoting the growth of probiotics and effectively inhibiting the growth of intestinal pathogenic bacteria such as Bacillus cereus and Escherichia coli. GG also enhances tolerance to adverse gastrointestinal conditions and can introduce probiotics, producing high concentrations of lactic acid in the culture medium, highlighting its potential as a functional food additive.
 
 
Market Prospects of Glyceryl Glucoside
 
Glyceryl glucoside is a colorless to light yellow liquid that is easily soluble in water, glycerol, and certain organic solvents. Its molecular weight is remarkably small, at only 254 Da, allowing it to penetrate directly into the dermis layer of the skin. This enables it to exert multiple physiological effects, improve various skin issues, and provide comprehensive, three-dimensional repair. In contrast, hyaluronic acid, known as the king of hydration, has a larger molecular weight, which highlights the greater potential for developing glyceryl glucoside. Hyaluronic acid boasts a 50-year history, with a market size reaching hundreds of billions.
 
With advancements in glyceryl glucoside synthesis technology, industrial production has been achieved through "bioenzymatic catalytic synthesis," with production capacities reaching several to tens of tons per year. In recent years, market demand has grown rapidly, and the application field of glyceryl glucoside is expected to expand from cosmetics to food, health products, and medicine, offering a broader range of applications.
 
 
Glyceryl Glucoside Use Cases
 
Nursing Lotion Series
Revitalizing Protein Massage Lotion:Enriched with glyceryl glucoside, this active moisturizer offers moisturizing, antioxidant, soothing, and repairing properties.
 
Hyaluronic Acid Water Light Massage Lotion contains glyceryl glucoside and hyaluronic acid, providing deep hydration and skin nourishment.
 
Soothing and Rejuvenating Ice Crystal:Infused with glyceryl glucoside, this product offers moisturizing, antioxidant, soothing, and repairing effects.
 
Niacinamide Vitamin C Body Lotion:Formulated with glyceryl glucoside, it provides moisturizing, antioxidant, soothing, and repairing benefits. Additionally, it contains glycerin, niacinamide, allantoin, and other ingredients to moisturize and care for the skin all over the body.
 
Baby Eczema Care Lotion
Glyceryl Glucoside Addition Amount
Glycerol glucoside 0.001-5% (by mass fraction)
Ingredients
Squalane, Dimethicone, Cetearyl Alcohol, PEG 100 Stearate, Glyceryl Stearate, Coco-Glucoside, Vitamin E, Dimethiconol, Water, Butylene Glycol, Glycerin, Propylene Glycol, Hydroxyacetophenone, 1,2 Hexanediol , Xanthan Gum, Allantoin, Sodium Hyaluronate, Polyacrylamide, C13 14 Isoparaffin, Laureth- 7, Stephania Tetrandra Extract, Phenoxyethanol and Hydrolyzed Sodium Hyaluronate
 
Anti-wrinkle series
The Energizing Fresh-Faced Line - Reducing Firming Light Cream, proudly featuring the brand name PROYA, incorporates glyceryl glucoside among its key components. Its formula also encompasses glycerin, 1,3-propylene glycol, cyclopentasiloxane, cetearyl alcohol, betaine, and various other ingredients. This cream boasts hydrating, antioxidant, calming, and restorative properties.
 
The Elastin Anti-Wrinkle Firming Serum, enriched with Glyceryl Glucoside, offers a comprehensive solution with hydrating, antioxidant, soothing, and reparative benefits.
 
The Blue Copper Peptide Anti-Wrinkle Essence is a potent blend that includes glyceryl glucoside, butylene glycol, tetrahydromethylpyrimidine carboxylic acid, parahydroxyacetophenone, tripeptide-1 copper, panthenol, xanthan gum, 1,3-propylene glycol, hydrolyzed collagen, and phenoxyethanol, among its carefully selected ingredients.
 
The Bifida Yeast Anti-Wrinkle Essence features glyceryl glucoside, bifida yeast fermentation product lysate, p-hydroxyacetophenone, acrylates/C10-30 alkyl acrylate crosspolymer, arginine, 1,2-pentanediol, and a host of other carefully curated components to address wrinkles and promote skin health.
 
Moisturizing, whitening and anti-wrinkle composition
Glycerol glucoside addition amount (percentage)
Glyceryl glucoside 0.40-0.80%
composition
Diguanosine tetraphosphate: 0.0015-0.01%, Hexapeptide-9: 0.00005-0.0005%, Sodium hyaluronate (1.5 million): 0.01-0.03%, Sodium hyaluronate (10,000): 0.02-0.06%, Niacinamide: 1.5-3.00%, The rest is water
 
Facial mask series
The elastic whitening mask incorporates glyceryl glucoside, a potent moisturizer renowned for its hydrating, antioxidant, soothing, and repairing properties. It further comprises a diverse array of components like glutathione, tranexamic acid, sodium benzoate, and soluble collagen, each tailored to deliver unique benefits like antioxidant protection, spot reduction, skin brightening, intense hydration, firming, and calming effects.
 
The whitening and spot-correcting moisturizing mask is formulated with glyceryl glucoside as its cornerstone, and is further enriched with sodium hyaluronate and purslane extract to amplify its hydrating, antioxidant, soothing, and reparative benefits.
 
The whitening and freckle-targeting mask is formulated with a blend of glyceryl glucoside, niacinamide, triethanolamine, α-arbutin, parahydroxyacetophenone, hydroxypropyl tetrahydropyrantriol, tetrahydromethylpyrimidine carboxylic acid, fullerene, hydroxydecyl ubiquinone, and PEG-40 hydrogenated castor oil, each carefully selected to address specific skin concerns.
 
The refreshing cool whitening mask features a rich blend of ingredients, prominently glyceryl glucoside, niacinamide, tranexamic acid, and sodium hyaluronate, among others, designed to provide a soothing and brightening experience.
 
Facial mask liquid
Glyceryl Glucoside Addition Amount
Glyceryl glucoside: 0.1-3 parts
Composition (parts by weight)
Propylene glycol: 1-10 parts, Hexylene glycol: 0.1-1 parts, Yeast amino acids: 0.1-5 parts, Sodium hyaluronate: 0.01-3 parts, Modified starch: 0.01-3 parts, Carnosine: 0.01-3 parts, The balance is ultra-low molecular water
 
Skin Beauty Series
The Double Anti-Brightening Essence is enriched with glyceryl glucoside, a versatile ingredient renowned for its moisturizing, antioxidant, soothing, and repairing properties. It also boasts a blend of other potent active ingredients, including niacinamide and tetrahydromethylpyrimidine carboxylic acid, formulated to deliver a holistic approach to skin care, addressing nourishment, repair, hydration, anti-aging, firming, and calming.
 
The Zhenmei Rejuvenating Skin Kit features glyceryl glucoside alongside sodium hyaluronate, acetylcysteine, glutathione, and an array of other carefully selected ingredients, designed to work in synergy for optimal skin rejuvenation.
 
The Time-Relieving Skin Essence Oil incorporates glyceryl glucoside along with tocopherols, niacinamide, and acetyl hexapeptide-8, among other ingredients, to create a luxurious formula that addresses various skin concerns while providing a pampering experience.
 
The Porcelain Skin Beauty Essence Oil is a blend of carefully curated ingredients, including glyceryl glucoside, butylene glycol, glycerin, tetrahydromethylpyrimidine carboxylic acid, and gentiana scabra root extract, all working together to enhance skin's radiance and overall health.
 
Skin repair composition
Recipe 1
Lyophilized powder: solvent = 1: (1-5) (mass ratio)
Lyophilized powder composition (by mass percentage): glyceryl glucoside: 1-20%, acetyl hexapeptide-8: 0.2-30%, oligopeptide-1: 0.01-30%, purslane extract: 1-10%, aloe extract: 0.1-10%, ceramide: 0.01-1%, betaine: 2-10%, mannitol: 20-40%; solvent composition (by mass percentage): hyaluronic acid: 0.2-1.0%, vitamin E: 2-5%, collagen: 0.01-5%, deer glue active protein: 0.1-10%, with the remainder being water.
Recipe 2
Composition ratio
Glyceryl glucoside 0.1 to 1 part
Phase A raw materials include: 43.5-88 parts water, 0.5-5 parts glycerol, and 0.0011-0.1 parts sodium hyaluronate. Phase D raw materials include: 2-10 parts water, 1-6 parts panthenol, and 0.1-1 parts glyceryl glucoside. Phase E raw materials include: 2-10 parts water, 0.002001-0.3 parts ceramide, 0.001-0.1 parts phytosphingosine, and 0.001-0.1 parts cholesterol. Sodium hyaluronate, panthenol, and ceramide work synergistically to enhance the skin's moisture retention capabilities.
 
Sunscreen Series
The hydrating sunscreen is formulated with a blend of nourishing ingredients, including glyceryl glucoside, sodium hyaluronate, hyaluronic acid, dipotassium glycyrrhizinate, allantoin, purslane extract, and artemisia annua extract, to provide comprehensive protection against UV rays while keeping skin moisturized and nourished.
 
This sunscreen boasts a comprehensive list of ingredients, featuring glyceryl glucoside, lactobacillus ferment lysate, 1,2-hexanediol, ethylhexyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine, methyl trimethicone, niacinamide, carbomer, adenosine, disodium EDTA, and arginine, all working together to shield skin from harmful UV rays and maintain its health.
 
The Beauty Rejuvenating Sunscreen Spray SPF50+ is enriched with glyceryl glucoside, sodium hyaluronate, and ceramide NP, offering advanced protection against UV damage while promoting skin rejuvenation and hydration.
 
Sunscreen composition
Glycerol glucoside addition amount
1.00-3.00% (mass percentage)
Element
Octocrylene-encapsulated silk protein solution, ethylhexyl methoxycinnamate-encapsulated silk protein solution, glycerin, butylene glycol, trehalose, PEG-7 glyceryl cocoate, a mixture of phenoxyethanol and 1,2-caprylyl glycol, and water
 
Cleansing Soap Series
Sulfur Multi-Effect Bath Soap contains glyceryl glucoside , which mainly plays the role of moisturizing, anti-oxidation, soothing and repairing in the product.
 
Environmentally friendly soap
Glycerol glucoside addition amount
Glyceryl glucoside (concentration not provided)
Composition (mass percentage)
Olive oil: 10%-15%, coconut oil: 40%-50%, palm oil: 20%-30%, bitter orange oil: 10%-20%, sodium hydroxide: 14%-16%, purified water: 10%-20%, GS: 0.5%-5%, plant protease: 1%-5%, natural plant antioxidant extract: 0.2%-0.8%, lemon essential oil: 1%-2%, VE: 0.1%-0.5%.
 
Hair Growth Series
The herbal scalp care essence fuses natural ingredients like glyceryl glucoside, palmitic acid, lecithin, and glycolipids, offering a deep hydration, antioxidant defense, soothing comfort, and reparative nourishment for the scalp. With a low acne-risk formula, a soothing fragrance, and a double-moisturizing boost from 1,2-pentanediol and 1,2-hexanediol, it's further fortified with parahydroxyacetophenone for all-around scalp health protection, rejuvenating your scalp's natural vitality.
 
The scalp balancing and revitalizing essence combines multiple moisturizing and reparative agents, including glyceryl glucoside, glycerin, and panthenol, with natural hydrators like 1,2-hexanediol and aloe extract. It also incorporates antioxidant and anti-aging components like parahydroxyacetophenone and placental protein, complemented by soothing and healing powers from β-glucan and Centella asiatica extract. Enhanced with maltodextrin for stable emulsification, phenoxyethanol for preservative safety, and madecassoside, ethylhexylglycerin, and asiatica glycoside for amplified antioxidant and calming effects, this essence comprehensively balances and revitalizes scalp health.
 
The rice water puree hair care lotion is enriched with additional ingredients such as glyceryl glucoside, glyceryl laurate, polydimethylsiloxane alcohol, and hydrolyzed keratin, providing a nourishing and flexible treatment for your hair.
 
The anti-hair breakage, nourishing, smooth, and shiny shampoo boasts a blend of precious plant extracts and high-performance active ingredients, including glyceryl glucoside, which deeply hydrates, resists oxidation, and offers a soothing and reparative experience, leaving your hair feeling nourished, smooth, and radiant.
 
Hair growth liquid
Composition ratio
1-5 parts of glyceryl glucoside, 5-22 parts of auxiliary materials, and the rest is water (based on 100 parts by weight)
stabilizer
Sodium hyaluronate, γ-polyglutamic acid, carboxymethyl chitosan, hydroxyethyl starch
moisturizer
Glycerin, 1,3-butylene glycol, propylene glycol, urea
Scalp absorption enhancer
Laurocapram, dimethyl sulfoxide, peppermint oil
Antioxidants
Citric acid, tartaric acid, ascorbic acid
 
Patent for wrinkle-removing products
Cream
Glyceryl glucoside: 0.8%, squalane: 10%, methylphenyl polysiloxane: 4%, hydrogenated palm kernel oil: 0.5%, hydrogenated soybean lecithin: 0.1%, polyoxyethylene sorbitan monostearate (20E.O.): 1.3%, sorbitan monostearate: 1%, glycerin: 4%, methyl paraben: 0.1%, carboxyvinyl polymer: 0.15%, purified water: balance (amount based on the total amount being 100), arginine (1% by mass aqueous solution): 20%, niacinamide: 6%.
Toner
Glyceryl glucoside: 0.3%, ethanol: 15%, polyoxyethylene (40E.O.) hydrogenated castor oil: 0.3%, fragrance: 0.1%, purified water: balance (total amount set to 100), citric acid: 0.02%, sodium citrate: 0.1%, glycerin: 1%, hydroxyethyl cellulose: 0.1%, niacinamide: 5%
Emulsion foundation
Glyceryl glucoside: 0.2%, squalane: 5%, cetyl alcohol: 2%, glyceryl tri-2-ethylhexanoate: 2.5%, methylparaben: 5%, lipophilic monostearate glyceryl: 1%, propylene glycol: 11%, sucrose fatty acid ester: 1.3%, purified water: balance (total amount set to 100), titanium oxide (pigment grade): 1%, ferric oxide: 0.1%, yellow iron oxide: 0.4%, micronized titanium oxide: 5%, micronized zinc oxide: 3%, fragrance: 0.1%, niacinamide: 4.5%.
Water-in-oil moisturizer
Glyceryl glucoside: 0.6%, liquid paraffin: 30%, microcrystalline wax: 2%, petrolatum: 5%, diglyceryl oleate: 5%, sodium chloride: 1.3%, potassium chloride: 0.1%, propylene glycol: 3%, 1,3-butylene glycol: 5%, methyl paraben: 0.1%, niacinamide: 3.5%, purified water: balance (total amount set to 100), fragrance: 0.1%