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Application of the Multi-Armed PEG Derivative Hydrogels

Time:2023-11-23 Hits:361
PEG水凝胶
The raw materials for hydrogels include polyethylene glycol (PEG), polyacrylamide (PAA), polyacrylic acid (PAAc), gelatin, sodium alginate, etc. In medical devices, PEG derivatives primarily exhibit a multi-armed structure. Due to their relatively large molecular weight, they can form hydrogels and are primarily used in surgical sutures, hemostasis, and assistance in tissue regeneration and wound healing.
 
PEG Modification Agents for Hydrogel Production typically possess functional groups such as -OH, -COOH, -SH, -NH2, -AC, -NHS active esters, anhydrides, and esters. These groups can undergo condensation reactions with other compounds, forming cross-linked structures and producing hydrogels with high water solubility and biocompatibility.
 
 
Applications of PEG Hydrogels:
Research progress in PEG hydrogels has been rapid, spanning biomedical, tissue engineering, and drug delivery fields. Compared to other raw materials, PEG-produced hydrogels exhibit superior biocompatibility, biodegradability, and tunability.
 
The future market outlook for PEG hydrogels is expansive. As the demand for health and beauty products continues to rise, the applications of PEG hydrogels in medical, biotechnology, cosmetics, and other fields are expected to grow. With ongoing technological advancements and expanding application domains, the performance and applications of PEG hydrogels will continue to improve and innovate, presenting significant market potential.
 
PEG hydrogels find application in drug delivery systems, tissue engineering, cell culture, and biosensors. In drug delivery systems, PEG-PLA hydrogels can serve as carriers for controlling drug release rates. In tissue engineering, PEG-DA hydrogels can act as scaffold materials for cell culture and tissue repair. In biosensors, PEG-MA hydrogels can function as the sensitive layer for detecting biomolecules.
 
 
Multi-Armed Polyethylene Glycol:
Multi-Armed Polyethylene Glycol (MA-PEG) can be used to produce hydrogels. MA-PEG, a unique PEG modification agent, differs from linear PEG by having multiple PEG branches, forming a more complex network structure, thereby enhancing the stability and mechanical strength of hydrogels.
 
In addition to multi-armed PEG, other PEG modification agents can also be used to produce hydrogels, such as Linear Polyethylene Glycol (L-PEG), Amphiphilic Polyethylene Glycol (A-PEG), etc. The number of branches in multi-armed PEG used for hydrogel production can be four or more, such as Tetra-Arm Polyethylene Glycol (4-Arm PEG) and Octa-Arm Polyethylene Glycol (8-Arm PEG).
 
 
List of Multi-Armed PEG Derivatives:
货号
品名
结构
AYC1246B
4-Arm-PEG-OH, MW 5K
4ArmPEG Hydroxyl
 
ECS1992A
4-Arm-PEG-OH, MW 10K
ECS2013A
4-Arm-PEG-OH, MW 20K
ECS4153A
4-Arm-PEG-AC, MW 2K
4Arm PEG Acrylate
 
ECS2028A
4-Arm-PEG-AC, MW 5K
ECS44557A
4-Arm-PEG-AC, MW10K
ECS4261A
4-ArmPEG-NH2, MW 2K
4Arm PEG Amine
 
ECS4093A
4-Arm-PEG-NH2, MW 5K
ECS4260A
4-Arm-PEG-NH2, MW 10K
ECS2120A
4-Arm-PEG-NH2, MW 20K
ECS4087A
4-Arm-PEG-COOH, MW 2K
4Arm PEG Carboxyl
 
ECS4265A
4-Arm-PEG-COOH, MW 5K
ECS4367A
4-Arm-PEG-CHO, MW 2K
4Arm PEG Aldehyde
 
ECS4221A
4-Arm-PEG-CHO, MW 5K
ECS4178A
4-Arm-PEG-CHO, MW 10K
ECS4358A
4-Arm-PEG-CHO, MW 20K
ECS4285A
4-Arm-PEG-Mal, MW 2K
4Arm PEG Maleimide
 
ECS4266A
4-Arm-PEG-Mal, MW 5K
ECS2073A
4-Arm-PEG-Mal, MW 10K
ECS4235A
4-Arm-PEG-Mal, MW 20K
ECS4177A
4-Arm-PEG-Mal, MW 40K
ECS4097A
4-Arm-PEG-SH, MW 2K
4Arm PEG Thiol
 
ECS1968B
4-Arm-PEG-SH, MW 5K
ECS4206A
4-Arm-PEG-SH, MW 10K
ECS2074A
4-Arm-PEG-SH, MW 20K
ECS4351A
4-Arm-PEG-N3, MW 2K
4Arm PEG Azide
 
ECS4340A
4-Arm-PEG-N3, MW 5K
ECS4215A
4-Arm-PEG-N3, MW 8K
ECS4216A
4-Arm-PEG-N3, MW 10K
ECS4201A
4-Arm-PEG-N3, MW 20K
ECS4360A
4-ArmPEG-HZ, MW 2K
4Arm PEG Hydrazide
 
ECS4323A
4-Arm-PEG-SC, MW 2K
4Arm PEG Succinimidyl Carbonate
 
ECS4286A
4-Arm-PEG-SC, MW 10K
ACS1803A
4-Arm-PEG-SCM, MW 10K
4Arm PEG Succinimidyl Carboxymethyl Ester
 
ECS4321A
4-Arm-PEG-SS, MW 10K
4Arm PEG Succinimidyl Succinate
 
ECS4359A
4-Arm-PEG-SS, MW 20K
ECS4229A
4-Arm-PEG-SG, MW 2K
4Arm PEG Succinimidyl Glutarate
 
ECS4230A
4-Arm-PEG-SG, MW 10K
ECS4369A
4-Arm-PEG-SG, MW 20K
ECS1998A
4-Arm-PEG-NCO, MW 5K
4Arm PEG Isocyanate
 
ECS1999A
4-Arm-PEG-NCO, MW 10K
ECS2000A
4-Arm-PEG-NCO, MW 20K
AYC1313B
8-Arm-PEG-OH, MW 10K
8Arm PEG Hydroxyl (hexaglycerol)
 
ECS2068A
8-Arm-PEG-OH, MW 20K
ECS4288A
8-Arm-PEG-NH2, MW 2K
8Arm PEG Amine
 
ECS4313A
8-Arm-PEG-NH2, MW 10K
ECS4287A
8-Arm-PEG-NH2, MW 20K
ECS4257A
8-Arm-PEG-NH2, MW 40K
ECS4269A
8-Arm-PEG-CHO, MW 10K
8Arm PEG Aldehyde
 
EYC1373A
8-Arm-PEG-N3, MW 10K
8 Arm PEG Azide
 
ECS4314A
8-Arm-PEG-HZ, MW 10K
8Arm PEG Hydrazide
 
ACS1802A
8-Arm-PEG-Mal, MW 10K
8arm PEG Maleimide
 
ECS4361A
8-Arm-PEG-Mal, MW 20K
ECS4179A
8-ArmPEG-Mal, MW 40K
ECS44556A
8-ArmPEG-Alk, MW 10K
8ArmPEG AlKyne
 
ECS4318-5g
8-Arm-PEG-AC, MW 10K
8ArmPEG-Acrylate
ECS4320A
8-Arm-PEG-AC, MW 20K
DCS4115A
8-Arm-PEG-SH, MW 10K
8arm PEG Thiol
 
ECS4467A
8-Arm-PEG-SH, MW 20K
ECS4466A
8-Arm-PEG-SH, MW 40K
ECS4270A
8-Arm-PEG-SC, MW 10K
8arm PEG Succinimidyl Carbonate
 
ECS4271A
8-Arm-PEG-SS, MW 10K
8arm PEG Succinimidyl Succinate
 
ECS4138A
8-Arm-PEG-SG, MW 10K
8arm PEG Succinimidyl Glutarate
 
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