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High Sensitivity Lipase Detection Substrate

Time:2024-03-11 Hits:195
Seebio Biotech offers a cutting-edge lipase substrate, 1,2-o-laurel-rac-glycerol-3-glutaric acid-(6-methylresorufin) ester, specifically designed for high sensitivity lipase detection in serum. With exceptional sensitivity and stability, ensure accurate results for your lipase assays.
 
For more product details, please contact us: service@seebio.cn or Phone: +86 21 58183719 or Wechat: +86 158 0195 7578
 
Detection Substrates and Measurement Principles:
 
1,2-o-Dilaurin-racemic-glyceryl-3-valerate-(6-methylresorufin) ester
 
 
Lipase hydrolyzes the substrate in a microemulsion containing co-lipase and bile acids, inhibiting the effects of other hydrolases and esterases. The resulting increase in absorbance due to the degradation of 6-methylresorufin ester is directly proportional to lipase activity in the sample.
 
 
Clinical Significance of Lipase:
 
Acute Pancreatitis: Lipase activity measurement aids in diagnosing pancreatic diseases, particularly acute pancreatitis, with high sensitivity (80%-100%) and specificity (84%-96%). It is particularly useful in later stages of the disease.
 
Acute Abdomen: Elevated serum lipase levels may indicate acute abdomen conditions.
 
Chronic Kidney Disease: Increased serum lipase levels may be observed in chronic kidney disease.
 
Differential Diagnosis between Mumps and Macroamylasemia: Serum lipase remains stable during mumps and macroamylasemia, making it a valuable differential diagnostic indicator.
 
 
Basic Product Information:
 
Name: 1,2-o-laurel-racemic-glycerol-3-glutaric acid-(6-methylresorufin) ester
Molecular Formula: C45H69NO8
Molecular Weight: 752.05
Melting Point: 29-31℃
pH Value: 7.0-7.5
Solubility: Soluble in polar organic solvents like n-propanol, ethyl acetate, dioxane, methanol, and dimethyl sulfoxide.
 
 
Product Advantages:
 
High sensitivity
Good stability
Suitable for various automated analyzers
Rigorously verified for many years by IVD manufacturers
Choose Seebio Biotech for a reliable lipase detection substrate with advanced features to elevate the precision of your lipase assays.
 
 
Product List:
Item number
 Name
Brand
Packaging
DYN0162B
lipase chromogenic substrate
1,2-o-laurel-rac-glycerol-3-glutaric acid-(6-methylresorufin) ester
Seebio
1g 10g
 
 
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