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β-cyclodextrin & derivatives

Time:2017-04-11 Hits:642

β-cyclodextrin & derivatives

Cat.No. Chinese name English name CAS Pack
122461 医药辅料:β-环糊精 Pharmaceutical excipients: 
β-cyclodextrin
68168-23-0 5kg
187901 食品添加剂:β-环状糊精 Food additives:
β-cyclodextrin
68168-23-0 5kg
187905 吡罗昔康-β环糊精 Piroxicam β-cyclodextrin 96684-39-8 25kg
122465 羟丙基-β-环状糊精 Hydroxypropyl - β - cyclodextrin 128446-35-5 50g
500g
10kg
187791 40% 羟丙基β环糊精水溶液 40% Hydroxypropyl - β–cyclodextrin aqueous solution 128446-35-5 25kg
200kg
122466 磺丁基醚β环糊精钠 Sulfobutyl ether beta cyclodextrin sodium 182410-00-0 15kg
122464 羟乙基-β-环状糊精 Hydroxyethyl - β - cyclodextrin 128446-32-2 50g
500g
10kg
122467 甲基-β-环状糊精 Methyl - β - cyclodextrin 128446-36-6 50g
500g
10kg
122469 葡萄糖基-β-环状糊精 Glucose - β - Cyclodextrin 7585-39-9 10kg


医药辅料:β-环状糊精
Pharmaceutical excipients: β-cyclodextrin 
【English name】β-cyclodextrin
【Alias】β-CD
【Molecular Formula】C42H70O35.xH2O
【CAS NO】68168-23-0
【Shape and properties】:White crystal powder

Applications
β-cyclodextrin is mainly used to increase the stability of drugs and prevent drug oxidation and decomposition to improve dissolution and bioavailability of the drug, It can be used to reduce side effects of drugs and mask drug odors as a new type pharmaceutical excipients,
In food manufacturing, β-cyclodextrin is mainly used to eliminate odors and flavor, improve the fragrance and color stability, enhance the emulsifying ability and moisture resistance, and to Improve the taste of food. It’s a good stabilizers, emulsifiers and flavoring agents in pharmaceuticals, food, cosmetics industry.

Packaging and storage:
Packaging materials meet national pharmaceutical packaging requirements. 
Specifications: 
1, high-grade cardboard box: 5kg × 4 / Box 
2, paper barrel: 5kg × 5 / barrel 
It should be stored in a cool dry place, the shelf life is 2 years 
It should be prevented from moisture, water, fire and pollution during transport

Technique Index

Terms Index
Appearance White crystal powder
Identification Perfect
Assay ≥96.0-102.0%
Acid and alkaki value 5.0-8.0
lose on drying ≤14.0%
Clearness and color of the solution Colorless, less than NO.2 turbidity liquid
Residue on igniton ≤0.1%
Reducing sugar ≤1%
Chloride Perfect
Special rotation +159o +164o
Total number of germ ≤1000 ceu/g
Total number of mould ≤100

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食品添加剂:β-环状糊精
Food additives: β-cyclodextrin
【English name】β-cyclodextrin
【Alias】β-CD
【Molecular Formula】C42H70O35.xH2O
【CAS NO】68168-23-0
【Shape and properties】:White crystalling powder, odourless

Applications:
In food manufacturing, β-cyclodextrin is mainly used to eliminate odors and flavor, improve the fragrance and color stability, enhance the emulsifying ability and moisture resistance, and to Improve the taste of food. It’s a good stabilizers, emulsifiers and flavoring agents in pharmaceuticals, food, cosmetics industry.

Packaging and storage:
Packaging materials meet national pharmaceutical packaging requirements. 
Specifications: 
1, high-grade cardboard box: 5kg × 4 / Box 
2, paper barrel: 5kg × 5 / barrel 
It should be stored in a cool dry place, the shelf life is 2 years 
It should be prevented from moisture, water, fire and pollution during transport

Technique Index:

Terms Index
Appearance White crystalling powder, odourless
Identification Perfect
Total sugar ≥86.5%
Assay ≥95%
Moisture content ≤13%
Ash content ≤0.5%

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吡罗昔康-倍他环糊精:Piroxicam β-cyclodextrin
【English name】Piroxicam β-cyclodextrin
【Alias】pyriproxyfen, Pyripropoxyfen; 2-(1-methyl-2-(4-PhenoxyPhenoxy)ethoxy)pyridine; Propiconazole
【Molecular Formula】C20H19NO3
【Molecular weight 】321.3698
【CAS NO】96684-39-8
【Shape and properties】:White crystalling powder, odourless

【Function and uses】: 
Piroxicam - Betacyclodextrin is also called inflammatory pain Meloxicam – Beta cyclodextrin, it’s produced by unique process according to the specific ratio of the pharmaceutical grade piroxicam and pharmaceutical grade beta-cyclodextrin inclusion, compared with Piroxicam, the inclusion has lower odor, greater stability, more stable drug release speed, which is mainly used in anti-inflammatory analgesic agents.

Packaging and storage:
Packaging materials meet national pharmaceutical packaging requirements. 
Specifications: 25kg / Box 
It should be stored and transported in a environment which be prevented from moisture, water, fire and pollution during transport.

Terms Index
Appearance White crystalling powder, odourless
Solution appearance 与标准溶液相符。 
Unanimous with standard solution
NH4+ ≤0.7%
2- amino pyridine ≤0.03%
Free drug content ≤0.5%
Acid and alkaki value 5.0-7.5
lose on drying ≤10.0%
Feldene content 8.0%-11.19%

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羟丙基β-环状糊精 Hydroxypropyl - β–cyclodextrin
【English name】Hydroxypropyl - β–cyclodextrin
【Alias】HP-β-CD, 2-hydroxypropylether
【Molecular Formula】:(C42H70O35)-HX+(C3H7O2)X
【Molecular weight 】1431-1806
【CAS NO】128446-35-5
【Shape and properties】:White powder, odourless,insipid innocent,sweet

Applications:
It’s mainly used in food, medicine and cosmetics industry, it can increase drug solubility, bioavailability and efficacy of the drug, It also can increase the curative effect when decreasing dosage, It can adjust or control the drug release rate, reduce the drug side effects and increase the stability. It is mainly used in injection and so on.

Packing and storage:
The packing meets national pharmaceutical packaging requirements
Specifications:
50g / bottle ,50g × 6 bottles / box ,500g / bottle
High-grade cardboard box: 10kg / box
Paper barrel: 10kg / barrel
Storage and transportation: It should be protected against moisture, water, fire and  pollution.
Polyethylene plastic bags, sealed for 2 years.

Technique index:

Terms Index
Appearance White powder, odourless,insipid innocent,sweet
Assay ≥98%
Degree of subsitution perfect
Moisture content ≤4.5%
Residue on igniton ≤1.5%
Heavy metal (Pb) ≤0.0025%
AS ≤0.0002%
Special rotation +159o +164o
The total number of germ ≤1000 ceu/g
Total number of mould ≤100
Germ causing disease none

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40%羟丙基倍他环糊精水溶液 
40% Hydroxypropyl - β–cyclodextrin aqueous solution
【English name】Hydroxypropyl - β–cyclodextrin
【Alias】HP-β-CD, 2-hydroxypropylether
【Molecular Formula】:(C42H70O35)-HX+(C3H7O2)X
【Molecular weight 】1431-1806
【CAS NO】128446-35-5
【Shape and properties】:40% hydroxypropyl-beta-cyclodextrin solution is modified products of Betacyclodextrin, the appearance is pale yellow transparent solution, the PH value is high.

【Functions】:
40% hydroxypropyl-beta-cyclodextrin solution is modified products of Betacyclodextrin, the appearance is pale yellow transparent solution, the PH value is high, It can get rid of odor. It contains many volatile ingredients to make it more stable and not easily broken. It makes it easily fusible for the insoluble component. It’s widely used in medicine, washing cosmetics and food industry, because the product adopts a new technology and it is liquid, thereby reducing the cost, the price is far lower than the powdered product.

【Packing and storage:
It’s packed in plastic drum
Specifications: 25 kg / drum, 200 kg / barrel, bulk
The storage and transportation should be anti-pollution.
The shelf life of sealed drum is six months from the date of manufacture.

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磺丁基醚倍他环糊精钠: 
Sulfobutyl ether beta cyclodextrin sodium
【English name】sulfobutyl ether beta-cyclodextrin sodium 
【Alias】Sodium sulfobutylether β-cyclodextrin; SBE7-beta-CD;
【Molecular weight】: 2200
【CAS NO】182410-00-0
【Shape and properties】:light yellow or white powder or similar

Function and uses】: 
Sulfobutyl ether beta-cyclodextrin sodium is sulfonated modified sodium salt of Betacyclodextrin, It’s also called butyl ether Betacyclodextrin thiosulfate sodium. The appearance is light yellow or white powder, it’s our new developed new type pharmaceutical preparations excipient products and be the best water-soluble cyclodextrin products for the current series of cyclodextrin. It’s mainly used as an insoluble drug carrier, which can significantly improve drug solubility and bioavailability. The product quality is excellent and has been quantities exported to India, the United States and other markets.

Packing and storage:
The packing meets the national pharmaceutical packaging requirements
Specifications: 15 kg / drum 
Storage and transportation: It should be protected against moisture, water, fire and  pollution.

Technique index

Terms Index
Appearance White powder or similar
Assay ≥98.0%
Degree of subsitution 5.0-8.0
lose on drying ≤4.5%
Residue on igniton ≤23%
Heavy metal (Pb) ≤20ppm
AS ≤4ppm
The total number of germ ≤1000
Total number of mould ≤100
Germ causing disease Not detected

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羟乙基-β-环状糊精 
Hydroxyethyl - β - cyclodextrin
【English name】Hydroxyethyl - β - cyclodextrin
【Alias】HE-β-CD
【Molecular formula】: C56H98O42 
【Molecular weight】: 1443.35
【CAS NO】128446-32-2
【Shape and properties】:White powder, odourless,insipid innocent,sweet


【Packaging and storage】
:Applications:
In medicine it can increase drug solubility and bioavailability, it can increase the drug efficacy or decrease the pharmaceutical dosage, it can adjust or control the drug release rate, reduce drug side effects, and enhance the stability of the drug. It is mainly used in oral liquid and has the highest safety.

The packing meets national pharmaceutical packaging requirements. 
Specifications: 
50g / bottle, 50g × 6 bottles / box, 500g / bottle
High-grade cardboard box: 10kg / box
Paper barrel: 10kg / barrel 
Storage and transportation: moisture-proof, waterproof, fireproof, anti-pollution. Sealed 2 years with Polyethylene plastic bags.

【Technique index】:

Terms Index
Appearance White powder, odourless,insipid innocent,sweet
Assay ≥98%
Degree of subsitution perfect
Moisture content ≤4.5%
Residue on igniton ≤2.0%
Heavy metal (Pb) ≤0.0025%
AS ≤0.0005%
The total number of germ ≤1000 ceu/g
Total number of mould ≤100
Germ causing disease not detected

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甲基-β-环状糊精 
Methyl - β - cyclodextrin
【English name】Methyl - β - cyclodextrin
【Alias】DM-β-CD
【Molecular formula】: C54H94O35
【Molecular weight】: 1303.3
【CAS NO】128446-36-6
【Shape and properties】:White powder, odourless,insipid innocent,sweet

【Packaging and storage:【Application:
In medicine it can improve the drug solubility and bioavailability, it can increase the 
Drug efficacy and decrease the pharmaceutical dosage. It can adjust or control the drug release rate, reduce the drug side effects, and enhance the stability of the drug, particularly it’s more effective for the water-soluble of oil-soluble molecules.

The packing meets national pharmaceutical packaging requirements
Specifications:
50g / bottle, 50g × 6 bottles / box, 500g / bottle
High-grade cardboard box: 10kg / box
Paper barrel: 10kg / barrel
Storage and transportation: moisture-proof, waterproof, fireproof, anti-pollution. Sealed bottled for 4 years, sealed 2 years in polyethylene plastic bags.

【Technique index:

Terms Index
Appearance White powder, odourless,insipid innocent,sweet
Assay ≥98%
Degree of subsitution perfect
Moisture content ≤4.5%
Residue on igniton ≤2.0%
Heavy metal (Pb) ≤0.0025%
AS ≤0.0005%
The total number of germ ≤1000 ceu/g
Total number of mould ≤100
Germ causing disease Not detected

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葡萄糖基-β-环状糊精 
Glucose - β - Cyclodextrin
【English name】Glucose - β – Cyclodextrin
【CAS NO】7585-39-9
【Shape and properties】:White powder, odourless,insipid innocent,sweet

Packaging and storage:Application:
1. In the field of medicine, it can improve the synthesis benefits of chiral drug and improve the drug quality;
2. In the field of food and spices, it can improve the stability and long-term efficacy of the nutritional molecules, it can mask or correct bad odor of the food nutrition molecules;
3. In the field of cosmetics, the stimulation of the molecular models to the skin and mucous tissue can be reduced , it can enhance the stability of the substance and prevent volatilization of nutrients, oxidation.

The packing meets national pharmaceutical packaging requirements
Specifications:
High-grade cardboard box: 10kg / box
Paper barrel: 10kg / barrel
Storage and transportation: moisture-proof, waterproof, fireproof, anti-pollution. Sealed for 2 years with polyethylene plastic bags

Terms Index
Appearance White powder, odourless,insipid innocent,sweet
Assay ≥98%
Degree of subsitution Perfect
Moisture content ≤4.5%
Residue on igniton ≤2.0%
Heavy metal (Pb) ≤0.0025%
AS ≤0.0005%
The total number of germ ≤1000 ceu/g
Total number of mould ≤100
Germ causing disease Not detected

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