Tipiracil

Code:
Grade:
CAS Number 183204-72-0
Molecular Formula C9H12Cl2N4O2
Molecular Weight 183204-72-0
Package：1 Kg/Bag
Function: thymidine phosphorylase inhibitor
Application: For research use only
Tags: Anti Tumor New Products

Summary
Properties
Product Detail

Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials.

TAS-102 is an antitumor agent composed of a combination of trifluorothymidine (FTD), a nucleoside that incorporates into DNA and inhibits a variety of genetic functions required for the proliferation of cancer cells, and tipiracil hydrochloride (TPI), an inhibitor of thymidine phosphorylase (which degrades FTD) that maintains an effective blood concentration of FTD. Tipiracil protects trifluridine from being broken down when taken orally.

Seebio also can supply Tipiracil intermediates as below:

PRODUCT NAME	CAS NO.	USAGE
5-Chloro-6-(chloromethyl)-2,4(1h,3h)-pyrimidinedione	73742-45-7	Tipiracil
3,4-dihydro-2H-pyrrol-5-amine hydrochloride (1:1)	7544-75-4	Tipiracil
6-(Chloromethyl)uracil	18592-13-7	Tipiracil

Thank you for your attention to Seebio Biotech (Shanghai) Co., Ltd.. If you’ve got any questions or comment, please

Seebio Biotech (Shanghai) Co., Ltd.
11-502, Lane 299, Bisheng Rd., Pilot Free Trade Zone, Pudong, Shanghai 201204, P.R. China
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Foreign Trade Department	Extension	E-Mail
Gloria Yang	6515	foodadd@seebio.cn
Leopard Jiang	6522	finechem@seebio.cn
Elisa Zhao	6521	reagent@seebio.cn
Isaac Gu	6516	pharmchem@seebio.cn
Michael Wu	6516	pharmchem2@seebio.cn

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Tipiracil